The FDA hasnt approved GLP-1 agonists for the treatment of T1D
However, a slight increase in OCD risk was observed, and no significant associations were identified for broad depression, major depressive disorder, anorexia nervosa, or self-harm
It should cite the FDA-approved indication, your specific clinical criteria, prior failed therapies with dates, and the clinical rationale for the requested medication
Given the increasing interest in the potential use of incretins in cardiovascular diseases, conducting randomized controlled trials in this direction is warranted
PLoS One 8 : e65646
These agonists not only enhance GLP-1 release but also suppress the expression of pro-inflammatory cytokines, including IL-2, IL-17a, interferon-, and TNF- (Yusta et al., 2015)